Fall 99 note: As in the past, I make no effort to use correct
symbolism on these past exam postings. You are responsible for 
correct symbolism.
I'm posting this to the web, because the newsgroup is so full
with essay claims that this would be difficult to find. Still,
I'm not including images.
I've put exams from fall 98 first.

Please don't print this out. It is huge!

This is fall 98 exam 3

 1. (3) Write the name of the deep groove on the line leading to 
       it at the top of the figure below. Write the names of the 
        structures on the other 2 lines leading to the structures 
       below.

 2. In the "steps" shown to the  
    right, which enzyme(s) 
    is/are used?
     A) DNA ligase
     B) DNA polymerase
     C) restriction enzyme
     D) reverse transcriptase

 3. In the "steps" shown to the 
    right, which enzyme(s) 
    is/are used?
     A) DNA ligase
     B) DNA polymerase
     C) restriction enzyme
     D) reverse transcriptase

 4. Which of the following sequences along a double stranded 
     DNA molecule may be recognized as a cutting site for a 
     particular restriction enzyme?
     A) AAGG   B) ACCA    C) AGTC    D) GGCC    E) TTTT
        TTCC        TGGT       TCAG       CCGG       AAAA

 5. The human genome project involves all of the following except the
     A) analysis of the genomes of other species
     B) sequencing of the entire human genome
     C) physical mapping of the chromosomes
     D) alteration of the human genome
     E) location of RFLP markers

 6. Impulses coming from a sensory receptor of the foot detecting the 
     tickle of a feather are carried to the cerebral cortex by 
     neuronal processes found in the
     A) Afferent division     B) CNS    C) Efferent division
     D) Parasympathetic division     E) Sympathetic division 

 7. Which of the following is not true of complementary DNA?
     A) It can be amplified by polymerase chain reaction.
     B) It can be used as a probe to locate a gene of interest.
     C) It can be used to create a complete genomic library.
     D) It does not contain the introns of eukaryotic genes.
     E) It is produced from mRNA using reverse transcriptase.

 8. Ascending pathways in the spinal cord convey
     A) commissural impulses       B) motor impulses
     C) sensory impulses      D) all of these

 9. Which of the following techniques would be most useful for 
    increasing the amount of DNA available for testing from a small
    sample of preserved tissue?
     A) electroporation       B) gel electrophoresis    
     C) in situ hybridization D) polymerase chain reaction (PCR)
     E) RFLP analysis

10. According to Marieb, the three phases of neuron development 
    occur in which order?
     A) cellular differentiation, migration, proliferation
     B) cellular differentiation, proliferation, migration
     C) migration, cellular differentiation, proliferation
     D) migration, proliferation, cellular differentiation
     E) proliferation, cellular differentiation, migration
     F) proliferation, migration, cellular differentiation

11. Which one or more of the choices is/are not part of the central 
     nervous system?
     A) a nerve         B) a tract  
     C) the brain    D) the spinal cord

12. The brain area most concerned  with equilibrium, body posture and 
    coordination of motor activity is the ____________________________

13. Write the names of the cells on the lines leading to them below.

14. Write the name of the nervous system structure
    on the line leading to it.

15. Which letter in
    the figure below
    best represents the 
    medulla oblongata?

16. Which lettered line best indicates a ventral root?
 

17. Which of the choices is/are primarily expressed in the fetus?


18. What process(es) led to the production of the current  
     globin genes from the ancestral beta globin gene?
     A) duplication
     B) mutation
     C) transposition
     D) all of the above

19. Chemical synapses are characterized by all of the following except
     A) a fluid filled gap separating the neurons
     B) ions flowing through protein channels from the 
        presynaptic to the postsynaptic neuron
     C) postsynaptic membranes bearing receptors that bind
        neurotransmitters
     D) the release of neurotransmitter by the presynaptic membranes

20. Describe the basis of biofeedback training.

21. Do you believe that osteogenin is an example of a protein 
    encoded by a homeotic gene?  Justify your answer with a 
    biological explanation.

22. Describe 2 possible causes of CVA's (strokes).


23. Mutant genes that predispose people to the development of cancer
     have been identified. Why is it that those genes only predispose
     people to cancer, rather than certainly causing cancer in every
     person who is born with them?

24. Define the job of central pattern generators, without using
     the words central, pattern and generators!

25. The ______________________________________ division 
    of the autonomic nervous system increases heart 
    rate, respiratory rate and blood pressure.

26. (3) Explain, using precise genetic terminology, why 2 parents of 
       average height can have an exceptionally tall child. Note that 
       this is a three point question. I want to see genotypes of both
       parents (2 points) and the child (1 point) using symbols that 
       you have precisely defined, following accepted rules of genetic
       symbolism.
        (Note, disregard any environmental contributions from diet, etc.)

27. Part of figure 15.3, "Hierarchy of  motor control", is shown below.
    Write the names of the featured  structures on the lines leading 
    to them.
          
28. Based upon the diagram below,
    the obturator nerve is supplied
    by (originates from) which roots? _________________________________
                                                                 
With your signature below, you indicate that the above answers and 
the work you did to prepare for this exam are your own work. You also 
indicate that you understand that you must send dpietras an e-mail 
from your ubunix account after you get your grade on this exam and 
before  Dec. 19, 1998 requesting to attempt the section(s) of the 
final exam of your choice on 12/21/98 starting at 11:45, and that you 
realize that your relevant hourly exam scores will then be set to zero.
 
Your signature: _________________________________________________________
I will record your grade out of 33 points here: _______/33   (32 required)
                         
I will record your total 
points for the course here: _______/100
I will record your letter grade for the course 
if you do NOT write any part of the final here: ____ 


here is the answer key for exam 3 fall 98

 1. Which of the choices is/are primarily expressed in the fetus?
D and E no partial credit lecture

 2. What process(es) led to the production of the current 
     G-gamma and A-gamma globin genes from the ancestral 
     beta globin gene?
     A) duplication
     B) mutation
     C) transposition
     D) all of the above
A and B no partial credit lecture
The transposition event has NO BEARING on the evolution of the gamma's
from the ancestral beta! That is, the transposition event did NOT change
the structure of the ancestral beta, os it had nothing to do with the
production of the gammas from the ancestral beta!

 3. Do you believe that osteogenin is an example of a protein 
    encoded by a homeotic gene?  Justify your answer with a 
    biological explanation.
Either Yes or No acceptable, if justified as below!
yes, because I can't imagine that just the presence of a single protein 
changes muscle cells into bone unless that protein is a regulator of many 
genes that need to have their expression changed in order to produce bone 
from muscle.
          or
no, because osteogenin apparently works from OUTSIDE the cell, while
homeotic genes clearly act in the nucleus of cells.
understanding lecture, although I admit that is a stretch!

 4. Mutant genes that predispose people to the development of cancer
     have been identified. Why is it that those genes only predispose
     people to cancer, rather than certainly causing cancer in every
     person who is born with them?
Because the development of cancer is a multi-step process, requiring
multiple genes to be mutated. Inheriting just one mutant gene is not
sufficient to certainly produce cancer.
homework CT & CA #4, chap 4 marieb, applied to this current material.
No, I don't know why I keep writing these sort of questions! The Bills
are in first place. I had a nice tuna sub for supper. I'm about as
happy as I get. And these questions just keep rolling off my fingers....

 5. (3) Explain, using precise genetic terminology, why 2 parents of 
average height can have an exceptionally tall child. Note that this
is a three point question. I want to see genotypes of both parents 
(2 points) and the child (1 point) using symbols that you have
precisely defined, following accepted rules of genetic symbolism.
(Note, disregard any environmental contributions from diet, etc.)
The A, B and C genes are involved in height in humans
(I will require at least 3. You may have many more. -1 if less than 3)
The alleles symbolized by upper case letters A,B,C are those that
produce tall heights.
The alleles symbolized by lower case letters a, b, c are those that
produce short heights.
So, parents that are average height and genotypically  Aa Bb Cc can 
produce a child that has the genotype AABBCC and would be exceptionally 
tall.
understanding lecture and homework and applying the principles.
You know, I'm listening to a bball game, and the team I'm rooting for
is winning a tournament right now, and these questions STILL keep
rolling off my fingers. I simply MUST stop this before the final!

 6. Which of the following sequences along a double stranded 
     DNA molecule may be recognized as a cutting site for a 
     particular restriction enzyme?
     A) AAGG   B) ACCA    C) AGTC    D) GGCC    E) TTTT
        TTCC        TGGT       TCAG       CCGG       AAAA
D lecture and # 8 chap 19

 7. Which of the following is not true of complementary DNA?
     A) It can be amplified by polymerase chain reaction.
     B) It can be used as a probe to locate a gene of interest.
     C) It can be used to create a complete genomic library.
     D) It does not contain the introns of eukaryotic genes.
     E) It is produced from mRNA using reverse transcriptase.
C lecture and # 2 chap 19

 8. In the "steps" shown to the right, 
    which enzyme(s) is/are used?
     A) DNA ligase
     B) DNA polymerase
     C) restriction enzyme
     D) reverse transcriptase
A and C Lecture and #1 chap 19 (0.5 each if none incorrect)

 9. In the "steps" shown to the right, 
    which enzyme(s) is/are used?
     A) DNA ligase
     B) DNA polymerase
     C) restriction enzyme
     D) reverse transcriptase
B lecture and #4 chapter 19, although I admit that you needed to 
THINK about the fact that more DNA had to be synthesized naturally 
by the plant as it grew! Why do I keep doing this? Is it that I am 
now looking forward to having a leftover half of a tuna sub for 
Thanksgiving dinner?  Hmmm, that just might be the explanation....
I would expect a student in my 300 level genetics courses in the
past to have answered A and B, so if you have A and B, that's OK.

10. Which of the following techniques would be most useful for 
    increasing the amount of DNA available for testing from a small
    sample of preserved tissue?
     A) electroporation       B) gel electrophoresis    
     C) in situ hybridization D) polymerase chain reaction (PCR)
     E) RFLP analysis
D.  Lecture and #4, chap 19 Campbell

11. The human genome project involves 
    all of the following except the
     A) alteration of the human genome
     B) analysis of the genomes of other species
     C) location of RFLP markers
     D) physical mapping of the chromosomes
     E) sequencing of the entire human genome
A lec and #5 chap 19 

12. Impulses coming from a sensory receptor of the foot detecting
    the tickle of a feather are carried to the cerebral cortex by
    neuronal processes found in the
     A) Afferent division
     B) CNS
     C) Efferent division
     D) Parasympathetic division
     E) Sympathetic division 
A and B (0.5 each if none incorrect) Lecture and that damn tuna sub...
At least I'm giving 0.5 point to those who forget B!

13. Write the names of the cells on the lines leading to them below.
satellite (upper) Schwann (lower) (0.5 each) lec and #2 chap 11

14. Which one or more of the choices is/are 
    not part of the central nervous system?
     A) a nerve          B) a tract
     C) the brain   D) the spinal cord
A lecture and #1 chap 11

15. Chemical synapses are characterized by all of the following except
     A) a fluid filled gap separating the neurons
     B) ions flowing through protein channels from the 
        presynaptic to the postsynaptic neuron
     C) postsynaptic membranes bearing receptors that bind
        neurotransmitters
     D) the release of neurotransmitter by the presynaptic membranes
B Lecture and Chap 11 # 6

16. According to Marieb, the three phases of neuron development 
    occur in which order?
     A) cellular differentiation, migration, proliferation
     B) cellular differentiation, proliferation, migration
     C) migration, cellular differentiation, proliferation
     D) migration, proliferation, cellular differentiation
     E) proliferation, cellular differentiation, migration
     F) proliferation, migration, cellular differentiation
F # 25 chap 11

17. (3) Write the name of the deep groove on the line leading to 
       it at the top of the figure below. Write the names of the 
        structures on the other 2 lines leading to the structures below.
Longitudinal fissure #12c chap 12
Corpus callosum lecture and #5 chap 12
thalamus lecture and #5 chap 12

18. Which letter best represents the medulla oblongata?
H lecture and # 5 chap 12

19. The brain area most concerned 
    with equilibrium, body posture and 
    coordination of motor activity is the ____________________________
cerebellum lec and #5 chap 12

20. Ascending pathways in the spinal cord convey
     A) commissural impulses
     B) motor impulses
     C) sensory impulses
     D) all of these
C lecture and # 6 chap 12

21. Describe 2 possible causes of CVA's (strokes).
Blockage of a blood vessel in/to the brain or
rupture of a blood vessel in the brain.
#29 chap 12

22. Which lettered line best indicates a ventral root?
J lecture and #12 chap 13

23. Based upon the diagram below,
    the obturator nerve is supplied
    by (originates from) which roots? ________________________________
L2, L3 and L4, no partial credit. Understanding lecture and #13 chap 13

24. The ___________________________ division of the autonomic nervous
    system increases heart rate, respiratory rate and blood pressure.
sympathetic
lecture and #2 chap 14

25. Write the name of the
    nervous system structure
    on the line leading to it.
vagus nerve
lecture

26. Describe the basis of biofeedback training.
The basis of biofeedback training is the use of technology to
make patients aware of changes within their bodies that they
normally have little or no awareness of, such as blood pressure.
#12 chap 14

27. Part of figure 15.3, "Hierarchy of motor control", is shown below.
    Write the names of the featured structures on the lines leading to 
them.
motor cortex or precentral gyrus (+0.5)
cerebellum (+0.5) lecture and homeworks

28. Define the job of central pattern generators, without using
     the words central, pattern and generators!
Segmental circuits of the spinal cord that control locomotion
("and oft-repeated motor activity")
lecture and #9 chapter 15
  
                                             
With your signature below, you indicate that the above answers and 
the work you did to prepare for this exam are your own work. You also 
indicate that you understand that you must send dpietras an e-mail 
from your ubunix account after you get your grade on this exam and 
before  Dec. 19, 1998 requesting to attempt the section(s) of the 
final exam of your choice on 12/21/98 starting at 11:45, and that you 
realize that your relevant hourly exam scores will then be set to zero.
 
Your signature: _____________________________________________
I will record your grade out of 32 points here: _______/32 
I will record your total 
points for the course here: _______/100
I will record your letter grade for the course 
if you do NOT write any part of the final here: ____ 





here is a crude answer key for the final section 3 of fall 98.
I don't have answer keys to distribute right after the exam, 
so at times the final exam answer key aren't very precise.

 1. Which of the choices is/are present in the adult genome?
F (all of the above) 
no partial credit lecture and application of #2 chapter 18 Campbell.
yes, I DO think the best students would have gotten this correct!

 2. Diagram of eye, asking for which line indicates the lens.
supplemental lecture about Smell, taste and vision

 3. The protein osteogenin is composed of
     A) cells    B) tissues   C) molecules     D) organs
     E) residues of amino acids    F) residues of fatty acids
     G) residues of nucleosides    H) residues of nucleotides
E understanding lecture notes, understanding supplemental homework
     from nutrition section, review of section 1. My prediction is
     that LOTS of people will get this wrong, because they refuse
     to understand the levels of biological organization, with
     chemistry as the basis.

 4. Specifically explain why chemicals in cigarette smoke cause lung 
     cancer, but explain this at the level a person in the general 
     public would understand the answer.
An answer: Chemicals in cigarette smoke can cause changes in the DNA, 
the hereditary information molecule, in all of our cells. When several 
of these changes accumulate in the DNA in lung cells, the function of 
the cell is changed so much that cancer is produced.
Incorrect answers will include terms like mutation, proto-oncogenes, 
oncogenes, etc, without having defined those words using simpler terms!
lecture and challenge #3, chap 18, campbell

 5. A woman has two children. One has type O blood, the other has
     type B blood. Which of the choices might correctly indicate
     the genotype of the mother? (no partial credit)
     A) IA IA  B) IB IB  C) ii
     D) IA i   E) IB i   F) IA IB
     G) all of the above
C, D, and E   modification of #6 chap 30

 6. A woman and a man have 2 children. One has blood type O, the other 
     has blood type B. What might be the blood type of the father? 
     (no partial credit)
     A) type A
     B) type B
     C) type O
     D) type AB
A, B and C   modification of #6 chap 30

 7. Define autosomes.
     "chromosomes that dictate most body characteristics" or
     All chromosomes except the X and Y or similar
#1 chap 30

 8. Which of the following sequences along a double stranded 
     DNA molecule may be recognized as a cutting site for a 
     particular restriction enzyme?
     A) AACGTT   B) CACCAC      C) TCAGTC      D) TTTTTT
        TTGCAA        GTGGTG         AGTCAG         AAAAAA
A lecture and modified # 8 chap 19

12. For whichever choice you made above, how frequently would
     a restriction enzyme that recognized that sequence cut
     human DNA? (That is, such a restriction enzyme would
     cut human DNA once every how many base pairs, on average?)
One every 4096 base pairs, on average.

 9. Which of the following is not true of complementary DNA?
     A) It can be amplified by polymerase chain reaction.
     B) It can be used as a probe to locate a gene of interest.
     C) It can be used to create a complete genomic library.
     D) It does not contain the introns of eukaryotic genes.
     E) It is produced from mRNA using reverse transcriptase.
C lecture and # 2 chap 19

10. In the "steps" shown to the right, 
    which enzyme(s) is/are used?
     A) DNA ligase
     B) DNA polymerase
     C) restriction enzyme
     D) reverse transcriptase
A and C Lecture, exam 3 and #1 chap 19 (0.5 each if none incorrect)

11. Which of the following has not yet been attempted or achieved, 
     as far as we know?
     A. Genetic testing for carriers of harmful alleles
     B. Introduction of genetically engineered genes into human gametes
     C. Prenatal identification of genetic disease genes
     D. Production of hormones for treating diabetes and dwarfism
     E. Production of subunits of viruses that may serve as vaccines
B # 6 chap 19 Campbell

13. The human genome project involves 
    all of the following except the
     A) alteration of the human genome
     B) analysis of the genomes of other species
     C) location of RFLP markers
     D) physical mapping of the chromosomes
     E) sequencing of the entire human genome
A lec and #5 chap 19 and exam 3

14. Which one or more of the choices is/are 
    part of the central nervous system?
     A) a nerve          B) a tract
     C) the brain   D) the spinal cord
B, C and D (no partial credit) lecture and modified #1 chap 11

15. What is the structural classification of the neuron below?
unipolar. lecture 

16. What is the name of the cell that 
    myelinates nerve fibers in the CNS? ___________________________
oligodendrocyte(s) lec and #2 chap 11

17. What is the importance of the "gaps" at the ends of the arrows below?
Action potentials "jump" from gap to gap, thus allowing fast propagation
of the action potentials.
Lecture.

18. What is the enzymatic function of acetylcholinesterase?
To degrade acetylcholine. #9 chap 11

19. Which letter indicates
     the temporal lobe?
lecture and #1 chap 12

20. Which lettered line in the diagram below indicates the 
corpus callosum?
lec and choice in #2 chap 12

21. Which lettered line in the diagram above indicates the hypothalamus?
lec and #2 chap 12

22. Which lettered line(s) in the diagram above indicates where the 
reticular formation is located?
lecture and #19 chap 12

23. Clearly explain what the terms paraplegia and hemiplegia mean, 
and how the two conditions differ.
paraplegia: motor/sensory loss in lower limbs
hemplegia: paralysis on one side of body.
(I added the "and how they differ" clause so that if a person answered 
"they both result in paralysis of 2 limbs" I could take off credit."

24. The most specific name 
    of the outermost covering 
    (labeled 1 in the diagram below) is the __________________________
dura mater #20 and 24, chap 12

25. Which lettered line in the diagram above 
    best indicates the/a ventral root?
lecture and # 24, chap 12

26. Define the term plexus, as used in the peripheral nervous system.
an area in which various "branches" from spinal nerves divide, merge and
redistribute into susequent "branches". or an "interlacing nerve network"
lecture and #13 chap 13

27. The optic nerve is a
     A) chemoreceptor         B) mechanoreceptor
     C) motor ending          D) photoreceptor
     E) none of the above
E lec and #9 chap 13. No, this was neither tricky nor detailed. It was
developed as I kept looking at a page of notes, needing to get a question, 
and I thought "Well, this will test whether they know the most 
fundamental definitions of the components of the PNS."

28. Explain why damage to peripheral nerve fibers is often reversible,
    whereas damage to CNS fibers rarely is.
the supporting cells are crucial. Particularly, the Schwann cells in
the PNS remain alive after the injury, and guide and stimulate regrowth 
of the axon. However, in the CNS, the oligodendrocytes around the 
injured axon die.
#11 chap 13

29. The ___________________________ division of the autonomic nervous
    system is "characterized" by the words "craniosacral outflow".
parasympathetic
lecture and #2 chap 14

30. Define analgesia.
     Reduced ability to feel pain, not accompanied by loss of 
consciousness.
RCT homework.

31. The neural machinery of the spinal cord is at the
     A) programs level
     B) projection level
     C) segmental level
C lecture and #3 chap 15

32. Damage to which of the areas eliminates consciousness?
none of the above. Lecture

33. EXTRA CREDIT ESSAY! (1 point for expression of an opinion
                        supported by a reasonably good English statement)
   The surprise ending of the material about using field programmable 
   gate arrays to develop an electrical "ear" was that back-engineering
   failed to learn how the "ear" worked! Only 32 of the gates were 
   working, and yet engineers could NOT figure out how the ear was working!
   In your opinion, will any of us in this room today learn how our 
   brains work to produce our consciousness? Why or why not?
No, not even if some of you live to be 300 years old!
Our brains are just too complicated, and there is NO LOGIC to our brains, 
they just evolved from random mutation of DNA instructions! Scientists
will try to think of logical ways that our brains work, and they will
fail, because evolution is not logical!
If anybody writes yes and supports it with a little essay, they
will also get the extra credit.
  
                                             
With your signature below, you indicate that the above answers and 
the work you did to prepare for this exam are your own work.
 
Your signature: ____________________________________________________
I will record your grade out of 32 points here: _______/33 (32 required) 





Fall 96 note: Remember that in the past, I put the questions in 
roughly chronological order. This year, the order will be scrambled.
this first exam is the fall 95 am exam 3 answer key.
note that at the end, I show what the grade entries on the
last page of your exam 3 will look like. that is, on the last
page of your exam 3, I will include what your letter grade will
be if you do not take the final exam.
I have left questions from chap 16 on this posting, even though I 
think we will only get through Chap 15 this fall 96 semester.
Remember that not all symbols can be properly shown in this
ascii text format. You will be responsible for the correct
symbols on the exams.
 6 ___    Apparently, your muscle cells are different from 
     your nerve cells mainly because they
     A) contain different genes    
     B) express different genes
     C) have different chromosomes
     D) use different genetic codes
     B lecture and #2 chap 18 
 7 ___    Which of these conditions is caused by recessive genes?
     A) Albinism         B) blood type A
     C) Down syndrome         D) Huntington's disease
     A lec and #5 chap 30
 8 ___    Which of the following tools of recombinant DNA technology 
     is incorrectly paired with its use?
     A) DNA ligase - enzyme that cuts DNA
     B) DNA polymerase - used in PCR to amplify sections of DNA
     C) electrophoresis - DNA sequencing
     D) restriction enzyme - production of RFLPs
     E) reverse transcriptase - production of cDNA
     A lec and #1 chap 19
 9 ___    Plants are more readily manipulated by genetic engineering
     than are animals because
     A) a somatic plant cell can grow into a complete plant
     B) more vectors are available for plant cells
     C) plant cells have larger nuclei
     D) plant genes do not contain introns
     E) recombinant genes can be inserted into plant cells
          by microinjection
     A lec and #3 chap 19  
10 ___    Which of the following has not yet been attempted or achieved?
     A) genetic testing for carriers of harmful alleles
     B) introduction of genetically engineered genes 
          into human germ cells
     C) prenatal identification of genetic disease genes
     D) production of hormones for treating human diseases
     B lec and #6 chap 19 
11 ___    The human genome project involves 
     all of the following except the
     A) alteration of the human genome
     B) analysis of the genomes of other species
     C) location of RFLP markers
     D) physical mapping of the chromosomes
     E) sequencing of the entire human genome
     A lec and #5 chap 19 
12 ___    Which of the following are part of the 
     central nervous system? (no partial credit)
     A) Brain            B) Spinal cord
     C) Spinal nerves         D) all of these
`    A and B lec and #1 chap 11
13 ___    Which type of neuron is most abundant?
     A) association      B) ependymal
     C) motor            D) sensory
     A lec
14 ___    Which of these is not a peripheral nerve 
     that comes from the brachial plexus?
     A) axillary         B) femoral
     C) radial           D) ulnar
     B #13 chap 13
15 ___    The neural machinery of the spinal cord is at the
     A) programs level
     B) projection level
     C) segmental level
     C lec and # 3 chap 15
19 (1) Explain the functional difference between hemoglobin 
     containing beta globin rather than alpha globin proteins.
     The 2 hemoglobins have different oxygen affinities. Lecture
20 (1) Marieb states that "the last phase of neuron development 
     is cellular differentiation of amitotic neuroblasts."
     What does amitotic mean? ("Circular" answers get zero credit.)
     Non-dividing  #25 chap 11
21 (1) Why is an EPSP excitatory?
     makes membrane potential less negative  lec
22 (1) Why do people with multiple sclerosis lose some ability
     to control skeletal muscles?
     The loss of myelination interferes with action potential
     propagation or "impulse conduction".  CT/A #4 chap 11
23 (1) How is the limbic system important in behavior?
     it is the emotional brain  lec
24 (1) Visual information is carried from the eye 
     toward the brain by the _________________________ nerve
                         optic lec
25 (1) Define analgesia.
     lessening of pain without loss of consciousness  RCT chap 15
     
     "pain relieving" +.5 (coma inducing would be pain relieving)
31 (1) The figure below 
     shows the procedure called ________________________________
                         amniocentesis
               fig 30.10A
32 (1) What is the name of the blackened 
      structure in the diagram below ? ______________________
                                   thalamus lec
                    12.9
33 (1) Which lettered region is the cerebellum? ______
               fig 12.8
34 (1) Which letter shows a ventral root? _____
                    fig 12.26
35 (1) Write the name of the blackened structure in the figure below
      on the line leading to it.
               sympathetic chain or sympathetic trunk lecture
               fig 14.4
Your signature: ______________________________
I will record your grade out of 35 points here: _______/35
I will record your course score out of 100 points here: ________/100
I will record your course letter grade 
if you do not take any of the final exam here: __________
This next exam is fall 95 PM exam 3 with answers.
 6 ___    Apparently, your muscle cells are different from 
     your nerve cells mainly because they
     A) contain different genes    
     B) express different genes
     C) have different chromosomes
     D) use different genetic codes
     B lecture and #2 chap 18
 7 ___    Which of these conditions exhibit polygene inheritance?
     A) albinism         B) blood type O
     C) color of skin         D) Down syndrome
     C lecture
 8 ___    Which of the following is not true of complementary DNA?
     A) It can be amplified by polymerase chain reaction.
     B) It can be used as a probe to locate a gene of interest.
     C) It can be used to create a complete genomic library.
     D) It does not contain the introns of eukaryotic genes.
     E) It is produced from mRNA using reverse transcriptase.
     C # 2 chap 19 and lecture
 9 ___    Plants are more readily manipulated by genetic engineering
     than are animals because
     A) a somatic plant cell can grow into a complete plant
     B) more vectors are available for plant cells
     C) plant cells have larger nuclei
     D) plant genes do not contain introns
     E) recombinant genes can be inserted into plant cells
          by microinjection
     A lec and #3 chap 19  
10 ___    Which of the following has not yet been attempted or 
     achieved?
     A) genetic testing for carriers of harmful alleles
     B) introduction of genetically engineered genes 
          into human germ cells
     C) prenatal identification of genetic disease genes
     D) production of hormones for treating human diseases
     B lec and #6 chap 19 
11 ___    The human genome project involves 
     all of the following except the
     A) alteration of the human genome
     B) analysis of the genomes of other species
     C) location of RFLP markers
     D) physical mapping of the chromosomes
     E) sequencing of the entire human genome
     A lec and #5 chap 19 
12 ___    Which of the following are part of the 
     peripheral nervous system? (no partial credit)
     A) cranial nerves   B) Spinal cord
     C) Spinal nerves         D) all of these
`    A and C lec and revised #1 chap 11
13 ___    Which cell type lines the brain cavities?
     A) astrocyte        B) ependymal     C) microglia
     D) oligodendrocyte  E) satellite cell     F) Schwann cell
     B #2 chap 11 and lecture
14 ___    Cerebrospinal fluid is formed by
     A) arachnoid villi  B) choroid plexuses
     C) dura mater       D) all of these
     B #4 chap 12 and lecture
15 ___    Ascending pathways in the spinal cord convey which impulses? 
     A) commissural      B) motor
     C) sensory               D) all of these
     C lec and #6 chap 12
16 ___    The optic nerve carries stimuli from
     A) chemoreceptors   B) mechanoreceptors
     C) photoreceptors   D) all of these
     C lecture
20 (1) Explain the function of homeobox protein domains.
     These sections bind to DNA    lecture handout
21 (1) What IS a node of Ranvier? 
      (NO credit for what a node of Ranvier DOES.)
     position at which there is a small gap in the myelin sheath or
     position at which the myelin sheath of 2 support cells abuts
     or similar wording.  Lecture
22 (1) Why is an IPSP inhibitory?
     makes membrane potential more negative  or
     it hyperpolarizes the postsynaptic membrane
     lec and #11 chap 11
23 (1) Localize the reticular formation in the brain.
      
      it runs through the center of the brain stem or
     "extends through central core of medulla, pons and midbrain"
     lecture and # 19 chap 12
24 (1) The vagus nerve innnervates organs of which body cavity(ies)?
     Thorax (0.5) and abdomen (0.5) or ventral (1) lecture
25 (1) The deficit of which neurotransmitter 
      is important in Parkinson's disease? ________________________
                                    dopamine CT/A # 3 chap 15
                                   L-dopa + zero
26 (1) Define analgesia.
     lessening of pain without loss of consciousness  RCT chap 15
     
     "pain relieving" +.5 (coma inducing would be pain relieving)
          basal  lecture
27 (1) The _______________________ cells of the 
       taste bud are capable of cell division. 
32 (1) The figure below 
     shows the procedure called ________________________________
                         chorionic villi sampling  lecture
               fig 30.10B
33 (1) Which letter is within the parietal lobe? _____
                                   lec and # 1 chap 12
          fig 12.8
34 (1) Which letter indicates one of the rami communicates? ____
                              lecture and #12 chap 13
35 (1) Place an X in a representation 
      of a ganglion.  Be sure that 
      your X is big enough to be 
      seen and has its crossover 
      precisely within the ganglion.
     lecture and #12 chap 13 fig 13.15b
This next exam is the fall 95 final exam section 3
 4 ___    Apparently, your muscle cells are different from 
     your nerve cells mainly because they
     A) contain different genes    
     B) express different genes
     C) have different chromosomes
     D) use different genetic codes
     B lecture and #2 chap 18 
 5 ___    The template used to make cDNA is a(n)
     A) DNA    B) mRNA   C) plasmid        D) restriction fragment
     B lecture and #10 chap 19
 6 ___    Which of these techniques is most useful for increasing the
     amount of DNA available for testing from a small DNA sample?
     A) electroporation       B) gel electrophoresis
     C) in situ hybridization D) polymerase chain reaction (PCR)
     E) RFLP analysis
     D lec and #4 chap 19
 7 ___    Chemical synapses are characterized by all of the following
     except
     A) a fluid-filled gap separating neurons
     B) ions flowing through protein channels from the presynaptic
          to the postsynaptic neuron
     C) postsynaptic membranes bearing receptors that bind 
          neurotransmitter
     D) the release of neurotransmitter by the presynaptic membranes
     B lec and # 6 chap 11
 8 ___    Which one of these choices symbolizes an amino acid 
     neurotransmitter?
                                      O
     A) H2N--CH2--COOH        B) H3C--C--O--CH2--CH2--N--(CH3)3
     
     C)  Tyr  Gly  Phe  Met        D) none of these
     A lecture
 9 ___    The brain area through which all the sensory input
     must travel to get to the cerebral cortex is the
     A) cerebellum       B) corpus callosum
     C) pons             D) thalamus
     D lec and # 2 chap 12
10 ___    Gustatory cells are stimulated by
     A) photons of light
     B) stretch
     C) substances in solution
     D) the movement of otoliths
     C lec and #4 chap 16
16 (1) Explain the functional difference between hemoglobin 
     containing beta globin rather than gamma globin proteins.
The 2 hemoglobins 
have different 
oxygen affinities.  Lecture
17 (3) A woman with blood type B has two children with the same man.
     One child has type O blood and the other has type A blood.
     (Note: if you use non-standard symbols in the answers below,
      be sure that you define your symbols to the right!)
revised #6 chap 30 IBi, IAi, type A 
IBi  What is the genotype of the mother?  ___________
IAi  What is the genotype of the father?  ___________
type A    What is the phenotype of the father? ___________  
     
18 (1) Define myelogram.
X-ray of the
spinal cord
after injection
of contrast medium
19 (3) List the structural components of the peripheral nervous
     system, and describe the function of each component.
sensory receptors +.5 
     respond to environmental 
     changes +.5
nerves +.5 
     transmit impulses +.5
motor endings +.5
     activate effectors 
 #9 chap 13
20 (1) Describe the basis of biofeedback training.
#12 chap 14
Making a subject aware
of normally subconscious
events
21 (1) What brain areas are involved in Parkinson's disease?
cta #3 chap 15
at least 2 of the following
substantia nigra
caudate nucleus
putamen nucleus 
     (lentiform nucleus)
or basal nuclei
25 (1) Which of these steps (1 though 6) 
     is performed by a restriction enzyme? ________
2 +.5 
&
3 +.5
2 & 4 = -1 (no credit)
4 & 5 = -1 (no credit)
26 (3) The diagram below shows a sensory neuron with associated items.
     A) What structural type of 
     neuron is shown in the diagram? ____________________________
unipolar. lec
     
     B) Name the item labeled B ____________________________
satellite cell lec
     
     C) Name the item labeled C ____________________________
nucleus lec
27 (1) Both questions refer to the diagram below.
B    Which lettered line indicates the corpus callosum? ______
O    Which lettered line indicates the medulla oblongata? ______
28 (1) Which lettered line
     on the figure of the
     spinal cord to the
     right indicates  
A    the cervical region? _____
29 (1) Which lettered roots in the diagram below
     contribute to the nerve at the end of the arrow? _______
E +.5
&
F +.5
E or F and any other -1 (no credit)
E and F and any other -.5
E and F and any others -1 (no credit)
Fall 1995 note: These past exam questions are a combination of a 
posting from past years of practie questions. At the end are the Fall 
1994 third exams and final section 3.
Note that in several cases there are genetic symbols that need italics 
and/or superscripts, which are not indicated on this posting, and which 
may not be accepted as your answers on this years exams.
This collection of questions are questions from past exams that are 
relevant to exam 3 in Fall 1993.
These questions are the relevant questions from third exams spring 1993
 7 ___A   Which of the following tools of recombinant DNA technology
          is incorrectly paired with its use?
          A) DNA ligase -enzyme that cuts DNA, creating "sticky ends"
          B) DNA polymerase - enzyme used in PCR to amplify DNA
          C) electrophoresis - DNA sequencing
          D) restriction enzyme - production of RFLPs
          E) reverse transcriptase - production of cDNA from mRNA
          (Lecture and Chap 19 Campbell, #1)
 8 ___C   Which of the following is not true of complementary DNA?
          A) It can be amplified by a polymerase chain reaction
          B) It can be used as a probe to locate a gene of interest
          C) It can be used to create a complete genomic library
          D) It eliminates the introns of eukaryotic genes
          E) It is produced from mRNA using reverse transcriptase
          (Lecture and Chap 19 Campbell, #3)
 9 ___C   The diagram below shows which structural type of neuron?
          (diagram as on class handout)
          
          A) bipolar       B) multipolar     C) unipolar   D) vagal
          (Lecture)
10 ___B   Chemical synapses are characterized by all of the following 
          except
          A) a fluid filled gap separating the neurons
          B) ions flowing through protein channels from the 
             presynaptic to the postsynaptic neuron
          C) postsynaptic membranes bearing receptors that bind
             neurotransmitters
          D) the release of neurotransmitter by the presynaptic 
             membranes
          (Lecture and Chap 11 # 6)
11 ___A   The primary motor cortex, Broca's area and the premotor 
          area are all located in which lobe?
          A) frontal        B) occipital       C) parietal  D) temporal
          (Chapter 12 #1)
12 ___A   Which one of the following regions is involved in control 
          of temperature, ANS reflexes, hunger and water balance?
          A) hypothalamus      B) medulla       C) pons       D) thalamus
          (Lecture and Chap 12 #2 part 3)
15 (1)    The process by which the possible developmental 
          fates of a particular cell become limited is called __
          determination (Lecture)
16 (1)    A permanent structural change in a gene is called a(n) _
          mutation (Chap 30, related clinical term)
17 (1)    A woman with type A blood is the mother of two children.
          One child has type O blood, the other has type B blood.
          What is the genotype of the mother? ___________ IAi
          (Chapter 30, #6)
18 (3)    Explain how recombinant DNA technology and related 
          techniques could be used to identify a rapist?  
(This is a three point question, and there are three short statements 
that will appear in my answer key that are a mininmally acceptable 
answer.  Don't think that you need to fill this page front and back 
with the answer!  I will subtract one point for each TERRIBLE statement 
that is wrong, out of order, irrelevant, etc)
          (Chap 19, #1 and indirectly lecture)
          (The three points below are the answers)
          1. Isolate DNA from a semen sample from the female victim
          2. Isolate DNA from a suspect under court order
          3. Perform RFLP analysis to see if the suspect's DNA is the
             same as the DNA taken from the victim, beyond reasonable 
             doubt.      
19 (1)    Which type of support cell lines the central 
          cavities of the brain and spinal cord? _______ependymal
          (Lecture and Chap 11, #2)
20 (1)    A bundle of neuronal processes in the PNS is called a(n) _
          nerve (lecture, homework indirectly)
21 (1)    The brain area through which all sensory input 
          must travel to get to the cerebral cortex is the _ thalamus
          (Lecture and Chap 12, #2 part 7)
22 (1)    An X-ray of the spinal cord after 
          injection of a contrast medium is called a(n) ____myelogram
          (Related clinical term Chapter 12)
23 (3)    List the structural components of the peripheral nervous
          system.
          Nerves, sensory receptors, motor endings
          (Lecture and Chapter 13, #9)
24 (1)    The sympathetic division of the ANS controls the muscles of 
     the iris of the eye, even though the sympathetic nerves emerge 
     from the thoracolumbar region of the spinal cord.  What structure 
     conducts the impulses UPWARD to the iris (and parallel to the    
     spinal cord)?
          (lecture) _______Sympathetic chain or trunk
25 (1)    The medical chart of a 68-year-old man includes the 
     following notes: "Slight tremor of right hand at rest; stony 
     facial expression; difficulty in initiating movements." Based on 
     your present knowledge, what is the diagnosis?
     (Lecture and Chap 15, CT&A #3) ___ Parkinson's (or dyskinesia)
28 (1)    Which of these genes in the beta globin gene 
          family shown below is expressed in the fetus?  _G & A gamma
          (no partial credit) (lecture)
          (figure 18.9 of Campbell 2E)
          
29 (1)    The process diagrammed 
          to the right with the ?  (This diagram was from the
          to the right of it is         basic strategy of genetic
                                   engineering diagram)
          called ________ transformation or genetic engineering _ 
          (lecture)
These questions are relevant questions from section 3 of the spring 93
final exam.
 6 ______ Metastasis is
          A) a mutation activates a protooncogene
          B) loss of contact inhibition
          C) remission of a tumor to a stable condition
          D) the spread of cancer cells from their site of origin
          E) transformation of a normal cell into a cancer cell
 7 ______ Alternate forms of a gene are called
          A) alleles   B) genotype   C) phenotype  D) sex chromosomes
     
 8 ______ Which of the following sequences along a double stranded 
          DNA molecule may be recognized as a cutting site for a 
          particular restriction enzyme?
          A) AAGG   B) ACCA    C) AGTC    D) GGCC    E) TTTT
             TTCC        TGGT       TCAG       CCGG       AAAA
 9 ______ The template used to make cDNA is
          A) a DNA probe    B) a plasmid    C) a restriction fragment
          D) DNA    E) mRNA
10 ______      Recombinant DNA technology has many medical applications.
          Which of the following has not yet been attempted or 
          achieved?
          A) introduction of genetically engineered genes into
             animal germ cells
          B) genetic testing for carriers of harmful alleles
          C) prenatal identification of genetic disease genes
          D) production of hormones for treating diabetes and 
             dwarfism
          E) production of subunits of viruses that may serve as 
             vaccines
          F) none of the above (that is, they have all been attempted
             or achieved)
11 ______ The cell diagrammed 
          to the right is
          A) bipolar
          B) multipolar
          C) unipolar
          D) none of the above
12 ______ Phagocytes in the CNS are called      A) astrocytes    
          B) ependymal cells    C) microglia    D) oligodendrocytes
          E) satellite cells    F) Schwann cells
13 ______ A patient has suffered a cerebral hemorrhage that has 
          caused dysfunction of the precentral gyrus of his right 
          cerebral cortex.  As a result, the patient 
          A) cannot voluntarily move her or his left arm or leg
          B) feels no sensation on the left side
          C) feels no sensation on the right side
          D) none of the above
16 (2)    The globin proteins made by the different globin genes are
          not structurally identical (that is, they have different 
          amino acid sequences).  You should also know two facts that
          indicate that the different globin proteins are 
          functionally different.  What are these two facts?
17 (2)    Why is the genetic change causing Huntington's disease 
          classified as dominant by clinicians but more properly 
          classified as incompletely dominant by geneticists?
18 (1)    What usually causes Down syndrome?
19 (1)    About how many EcoRI recognition sites are in the human
          genome? ____________________
20 (2)    List two ways in which the cerebellum is very similar to 
          the cerebrum.  Be sure one is an anatomical similarity and 
          the other is a functional similarity.
21 (1)    A collection of fascicles and blood vessels surrounded by
 
          tough connective tissue is called a(n) __________________
22 (2)    What organs does the vagus nerve innervate and what 
          physiological processes does it control?
23 (2)    Describe the basis and uses of biofeedback training.
27 (1) The clustered "coil"
     of cell bodies in the
     diagram to the right is
     called a(n) _______________
These questions are from the final exam from Fall 1992
1____     DNA is cleaved at specific base sequences by
     A) DNA ligase
     B) DNA polymerase
     C) Restriction enzymes
     D) Reverse transcriptase
     modified from #14 exam 3
2____     In recombinant DNA methods, the term "vector" refers to
     A) a DNA probe used to locate a particular gene
     B) a plasmid or other agent used to transfer DNA into a living 
          cell
     C) an RFLP marker
     D) the enzyme that cuts DNA into restriction fragments
     repeat from exam 3
3____     Which of the following is not a technique for introducing 
     recombinant DNA into host cells?
     A) electrophoresis 
     B) infection by Agrobacterium
     C) infection by bacteriophage 
     D) microinjection
     E) transformation using recombinant plasmids
     homework #2chapter 19, mentioned in lecture
4____     Which of the following is not true of complementary DNA?
     A) It can be amplified by a polymerase chain reaction.
     B) It can be used as a probe to locate a gene of interest.
     C) It can be used to create a complete genomic library
     D) It does not contain introns of eukaryotic genes.
     E) It is produced from mRNA using reverse transcriptase
     homework # 3 chapter 19
5____     Some of the possible ethical, social and legal issues attached to 
     the Human Genome Project are (chose the best answer):
     A) Discrimination in eligibility for insurance coverage
     B) Discrimination in employment due to genetic composition
     C) Stigmatization by society due to genetic composition 
     D) Tremendous depression upon learning of a genetic disease
     E) All of the above
     (from assigned reading and lecture discussion)
6____     Which of the choices is part of the peripheral nervous system?
     A) a nerve
     B) a tract
     C) the brain
     D) the spinal cord
     E) none of the above (that is, they are all part of the CNS)
     (revised exam 3)
7____     The cells that form myelin sheaths in the PNS are
     A) astrocytes       B) ependymal cells
     C) microglia        D) oligodendrocytes
     E) satellite cells  F) Schwann cells   (revised exam 3)   
8____     Cerebrospinal fluid is returned to the blood through
     A) arachnoid villi
     B) choroid plexuses
     C) dura mater
     D) all of these
     revised from exam 3
9____     Descending pathways in the spinal cord convey
     A) commissural impulses
     B) motor impulses
     C) sensory impulses
     D) all of these
     revised exam 3
10___     The parasympathetic nerve that regulates the heart and lung is 
     the
     A) abducens
     B) glossopharyngeal
     C) sympathetic trunk (or sympathetic chain)
     D) vagus
     E) none of the above
     revised exam 3
11___     The neural machinery of the brain involved in motor controls is 
     at the
     A) programs level
     B) projection level
     C) segmental level
     D) none of the above
     revised exam 3
Part 2, short answers (the point value of each question is in 
parentheses)
12 (1) A woman and man who lived their entire lives on Long Island had 
a child that suffers from Sickle-Cell Anemia.  They had never had any 
symptoms of the disease, and were terribly surprised by their child's 
illness. Why did they not have any symptoms, in spite of the fact that 
the gene is not completely recessive? (surprise) 
13 (3)  Three processes that appear to have been involved in the 
evolution of the beta globin gene family are 
14 (1) A restriction enzyme recognition sequence that is 4 base pairs 
in size appears once in every ____________________________ DNA base 
pairs on average.
15 (1)  The part of the diencephalon that is the gateway to the 
cerebral cortex is the ____________________________. 
16 (1) The sensory information from proprioceptors goes to the 
_____________ rather than the primary sensory cortex.
17 (1)  How is the RAS (reticular activating system) important in 
alertness? 
18 (1)  How is an EPSP different from an action potential? (note: there 
are at least three different acceptable answers.  1 is enough.)
19 (2) Describe what a central pattern generator is and what it does?
Part 3, diagrams (one point each)
                                                       
20 (1) Which one of the lines                               A
labeled A, B, C or D in
the diagrams to the right 
ends in the temporal lobe? _____ 
                                                                                          D --
                                        
                                          
                                                       
                                                       B
                                                       
                                                       C
21 (1) The area of the diagram
to the right that is circled
in red is the tract named the
_____________________________      (This was fig 12.8 with corpus
                               callosum are circled)
22 (1)  According to the diagram
of the lumbar plexus to the right,           (This diagram was fig 13.8)
which roots supply the femoral nerve?
These questions are from exam 3 in fall 1992. Remember, the seond 
edition of campbell was used then.
1__B_     Apparently, your muscle cells are different from your nerve cells
          mainly because they
     A) contain different genes
     B) express different genes
     C) have different chromosomes
     D) none of the above
     Homework # 2, chapter 18, end lecture 27
2__D_     Cancerous metastasis is
     A) a mutation activating a protooncogene
     B) loss of contact inhibition
     C) remission of a tumor to a stable condition
     D) the spread of cancer cells from their site of origin
     E) transformation of a normal cell into a cancer cell 
     Homework # 5 chapter 18, related to lecture 28 and previous 
     lectures
3__B_     In recombinant DNA methods, the term "vector" refers to
     A) a DNA probe used to locate a particular gene
     B) a plasmid or other agent used to transfer DNA into a living 
     cell
     C) an RFLP marker
     D) the enzyme that cuts DNA into restriction fragments
     lecture 31, homework #8, chapter 19
4__E_     The template used to make cDNA is
     A) a DNA probe
     B) a plasmid
     C) a restriction fragment
     D) DNA
     E) mRNA
     lecture 32 and homework #9, chapter 19
5__A_     The human genome project involves all of the following except the
     A) alteration of the human genome
     B) analysis of the genomes of other species
     C) location of RFLP markers
     D) physical mapping of the chromosomes
     E) sequencing of the entire nucleotide sequence of the human 
     genome.
     homework, #5, chapter 19 and lecture 33)
6__A_     Which of the following structures is not part of the central 
     nervous system?
     A) a nerve
     B) a tract
     C) the brain
     D) the spinal cord
     E) none of the above (that is, they are all part of the CNS)
     homework #1, chpater 11, lecture 34 and 37)
7__D_     The cells that form myelin sheaths in the CNS are
     A) astrocytes       B) ependymal cells
     C) microglia        D) oligodendrocytes
     E) satellite cells  F) Schwann cells      
     Lecture 34 and hw#2chap11
8__B_     Cerebrospinal fluid is formed by
     A) arachnoid villi
     B) choroid plexuses
     C) dura mater
     D) all of these
     (lecture 36 and homework #4, chap 12)
9_C_ Ascending pathways in the spinal cord convey
     A) commissural impulses
     B) motor impulses
     C) sensory impulses
     D) all of these
     (lecture 37 and homework #6 chapter 12)
10_D_     The sympathetic division of the autonomic nervous system
     A) increases blood pressure
     B) increases heart rate
     C) increases respiratory rate
     D) all of the above
     E) only A and B above.
     Homework # 2 chapter 14, associated with lecture 38)
11_C_     The neural machinery of the spinal cord involved in motor 
     controls is at the
     A) programs level
     B) projection level
     C) segmental level
     (lecture 39, homework #3, chapter 15)
Part 2, short answers (the point value of each question is in 
parentheses)
12 (1)  The mutant gene that produces four wings instead of two in 
flies is called ________bithorax________________. 
lecture 28 handout and lecture
13 (1)  A woman and man have a child that is albino. The parents both 
have normal pigmentation.  What is the probablity that their next child 
will be albino?  ____1/4______or 25%___. (surprise!)
extension of #5, chap 30, related to lec 29
14 (1)  DNA is cleaved at specific base sequences 
by_______________________. 
lecture 29, modified homework (chapter 19, #1 and 7)
15 (1)  An application of genetic engineering that could lead to the 
release more herbicide into the environment is 
16 (1)  Approximately how many base pairs are in the human genome? 
(lecture 32)
17 (1)   The prominent tract that connects the two hemispheres of the 
brain and is immediately below the longitudinal fissure is the 
(lecture 35)
18 (1)  The part of the diencephalon that is the gateway to the 
cerebral cortex is the ____________________. 
(lecture 36)
19 (1) The brain area most concerned with equilibrium, body posture and 
coordinatiion of motor activity is the __________________________
(lecture 36 and homework #2, chapter 12)
20 (1)  How is the limbic system important in behavior? (lecture 36 and 
homework #18, chapter 12)
21 (1)  How is a receptor potential like an EPSP? 
lecture 37 and homework, #10, CHAPTER 13) 
22 (2) In the cartoon above, rascal seems to be displaying a type of 
spinal reflex. Explain how a stimulus such as that administered in the
cartoon could lead to a response as shown without input from the brain. 
lecture 38
(This showed a Curious Avenue cartoon in which the child was scratching 
the dog, Rascals, rump, and then the dog would stomp its leg)
(Afferent impulse, synapse in cord, efferent impulse, synapse in 
muscle, 0.5 each)
Part 3, diagrams (one point each)
                                                       
23 (1)  Figure 12.7.  Which one of                               A
the lines labeled A, B, C or D in
the diagrams to the right 
ends in the occipital lobe? __C__ 
(Lecture 35)                                                                                   D --
                                        
                                          
                                                       
                                                       B
                                                       
                                                       C
24 (1)  According to the diagram
to the right, which roots supply
the median nerve?
_____________________________________
(lecture 37 and homework # 13, chapter 13)
This section is answers to questions above
Answers to section 3, spring 1993 final exam.
1. C (interstitial cells of the testes
2. A
3. This is meaningless for me to answer, 
since you can't see the diagram.
4. C
5. C
6. D
7. A
8. D
9. E
10. F
11.  This is meaningless for me to answer, 
since you can't see the diagram.
12. C
13. A
14.  a) The hormone HCG, Human Chorionic Gonadotropin
     b) So that it continues the hormonal stimulation of the uterine 
lining
15. Ossification
16. The 2 globins in adults (alpha and beta) are functionally different 
     because you do not see hemoglobin molecules with 4 beta globins or 
4 alpha globins, for example.  That is, 2 beta globins do not substitute 
for 2 alpha's in    adult hemoglobin.
     Also, fetal hemoglobin has a higher affinity for oxygen than adult 
hemoglobin
17. Clinicians see disease in the heterozygote
     Geneticists see a difference in phenotype between the heterozygote 
and homozygote diseased because homozygotes with 2 mutant genes are not 
seen, thus the mutations must be lethal in homzygotes.
18. Trisomy 21 (Interestingly, it really is trisomy 22.  Chromosomes 21 
and 22 are so similar in size that they were misinterpreted for a long 
time!)
19. 700,000
20. Anatomical: both convoluted (others obviously possible)
     Functional: Both have sensory and motor maps (others possible)
21. Nerve
22. Mostly thoracic and abdominal
     Heart rate, breathing, digestive system activity (and others)
23. Basis: patient allowed to monitor "involuntary" functions 
technologically, thus developing the ability to consciously control 
those functions To manage migraine headaches and stress
24.  This is meaningless for me to answer, since you can't see the diagram.
25.  This is meaningless for me to answer, since you can't see the diagram.
26.  This is meaningless for me to answer, since you can't see the diagram.
27. (Basal) Nucleus
These answers are from final exam Fall 1992
1. C, Restriction enzymes
2. B
3. A
4. C
5. E
6. A
7. F
8. A
9. B
10. D
11. A & B
12. They were never under oxygen stress (reduced oxygen concentration)
13. Duplication, transposition, mutation
14. 256 (one quarter to the fourth power)
15. Thalamus
16. Cerebellum
17. Various answers possible Inhibited by sleep centers was popular
18. EPSP is a graded potential
19. A CPG is a segmental circuit of the spinal cord that controls locomotion.
     CPGs produce rythmic muscular contractions 
          that pruduce normal patterns of locomotion 
20.  This is meaningless for me to answer, since you can't see the diagram.
21. corpus callosum
22. L2, L3, and L4 (this required you to understand how to "map" the 
origin of the nerve by tracing "upstream" from the nerve.)
This is the end of the answers section so far
The following is the key to the fall 1993 exam 3
 8 ___  Which is an example of a homeotic mutant gene?
       A) anterior/posterior       B) bithorax
       C) crystallin               D) differentiation
       E)   (epsilon) globin       F) fetal globin
       G) G & A gamma globins H) hemoglobin
          B. lecture handout.  
 9 ___  Which of the following sequences along a double-stranded DNA 
       molecule may be recognized as a cutting site for a particular 
       restriction enzyme?
       A) AAAA      B) AAGG      C) ACCA      D) AGTC      E) GGCC
          TTTT         TTCC         TGGT         TCAG         CCGG
          E #9, chap 19 Campbell and lecture
10 ___  Which of the following techniques would be most useful for 
       increasing the amount of DNA available for testing from a small
       sample of preserved tissue?
       A) electroporation          B) gel electrophoresis    
       C) in situ hybridization    D) polymerase chain reaction (PCR)
       E) RFLP analysis
          D.  Lecture and #4, chap 19 Campbell
11 ___  The Human Genome Project involves all of the following goals
       except
       A) altering the human genome
       B) the analysis of the genomes of other species
       C) the location of RFLP markers
       D) the physical mapping of the chromosomes
       E) the sequencing of the entire human genome
          A.  #5, chapter 19 Campbell 3E.
12 ___  Which of the following structures is not part of the central 
       nervous system?
       A) a nerve    B) a tract    C) the brain    D) the spinal cord
          A. lecture and #1, chap 11.
13 ___  Biogenic amine neurotransmitters include all but
       A) acetylcholine       B) dopamine         
       C) norepinephrine      D) serotonin
          A. #7, chap 11
14 ___  The diagram to the right shows the
       A) cerebellar motor cortex
       B) cerebellar sensory cortex               fig 12.10 right
       C) cerebral motor cortex
       D) cerebral sensory cortex. 
          D. lecture
15 ___  Cerebrospinal fluid is formed by
       A) arachnoid villi
       B) pineal gland
       C) choroid plexuses
       D) dura mater
          C lec and #4 chap 12
     
     
19 (2) A woman with blood type A has two children with the same man.  
      One child has type O blood and the other has type B blood.  
          What is the genotype of the mother?  __________ 
          What is the phenotype of the father? __________
     mother IA i         father type B (IB i gets zero credit)
     #6, chap 30 and (logical deduction from) lecture handout.
20 (1) Plants are more readily manipulated by genetic engineering 
than are animals because
     a somatic plant cell can grow into a complete plant
          #3, chapter 19, campbell and lecture
     certainly incorrect answers:
1. plant genes do not contain introns
2.more vectors are available for 
     transferring recombinant DNA into plants.
3.recombinant genes can be inserted into plant cells by microinjection
4.plant cells have larger nuclei. 
There may be other correct and incorrect answers given by those 
unaware of the connection between this question and the homework 
question.
21 (3) Introduction: Linda Yalem, who was a UB student training alone 
     for the New York City marathon, was raped and murdered in broad 
     daylight just off the bike path near campus. The murderer is 
     known to be the same assailant of several other women who 
     survived other attacks because DNA fingerprints from semen from 
     the murder scene and the other attacks are identical.  
     The question: Describe, in detail, the steps you need to do to 
     visualize the bar code-like DNA fingerprint pattern from a semen 
     sample. 
     Grading:  0.5 points per correct step.  
               0.5 points subtracted for each incorrect step.  
               0.5 points subtracted for each unnecessary step.  
          Minimum score is zero.  That is, if you enter 10 ridiculous 
          steps, you will still only lose 3 points, so don't be 
          afraid to attempt this question, but answer it precisely.
     Enter your answer below:
1. Isolate DNA from the semen  (isolate DNA from white blood cells -.5)
2. Treat the DNA with a restriction enzyme
     (a restriction enzyme is added to the three samples -.5)
3. Electrophorese the treated DNA  (to produce visible bands, -.5)
4. The DNA is blotted onto special paper
     (Denaturing the DNA is optional in answer.  If it is included,
      you will not lose points for saying by heating as described in 
      campbell 3E, but that is not the way it is in fact done.)
5. Add radioactive probe to paper (to visualize bands on paper -.5)
6. rinse away excess probe and autoradiograph paper to visualize bands 
     on the film.
     Mentioning PCR is likely to result in point deductions.
     Yes, this is going to be a nightmare to grade.  I'm looking 
forward to it.  The basic idea is that you will get basically nothing 
for copying descriptions to the procedures in Campbell, but if you 
understand the procedure well enough to realize the errors in the 
diagrams from Campbell and to apply that knowledge to a specific case 
of semen DNA fingerprints, you will easily get full credit. I hope. I 
hope I don't rationalize. 
     A previous exam question, WHICH WAS WORDED DIFFERENTLY, listed a 
three step answer like 
1) isolate DNA from semen from the crime scene, 
2) isolate DNA from the suspect, 
3) do RFLP analysis to compare them. 
THIS WAS NOT THE SAME QUESTION.  
THE ANSWER TO THIS QUESTION WAS AN 
ELABORATION OF BASICALLY POINT 3!  
Thus, this old answer got only 0.5 
points, that is, it did not include 5 
of the specific steps, and so 
lost 2.5 points.
     lecture and challenge question 1 Campbell 2E 
22 (1) Define plexus  Areas in which branches of spinal nerves are 
joining, redistributing and diving again. Lecture and #13, chap 13
23 (1) A viral inflammation caused by herpes zoster (the chickenpox 
virus), which invades the dorsal roots of spinal nerves and causes 
blisterlike skin lesions is called __________________shingles related 
clinincal term chapter 13
24 (1) The medical chart of a 68-year-old man includes the following 
notes: "Slight tremor of right hand at rest; stony facial expression; 
difficulty in initiating movements."  Based on your present knowledge, 
what is the diagnosis of the disease the man is suffering from? 
Parkinsons CT&A #3 chapter 15.
or
Amyotrophic lateral sclerosis is OK, at this level of study
26  (2) Both parts of this question refer to the diagram of a neuron in 
the peripheral nervous system below.
          A                   B
                    modified fig 11.2 E
     What is the name of the cell at the end of line A? ____Schwann
          lecture and # 2 and 15, chapter 11.
          Due to the abysmal level of most answers, we awarded
          0.5 point to the answer "cell body".
     What is the name of the structure 
     indicated by the oval at the end of line B?_________ the nucleus
               lecture
27 (2) In the diagram below depicting spinal cord anatomy, 
     the structure at the end of line A is _________________________
                    dorsal root ganglion lecture and #12 chap 13
                    "Dorsal root", "spinal nerve" and "ganglion"
                    all lost 1 point, and I won't budge on those.
                    We did accept "Dorsal foot ganglion" in the
                    spirit of the holidays!
     and 
     the covering at the end of line B is __________________________
                         dura mater (a bit of a surprise)
                         meninges lost 1 point.
28 (1) The nerve drawn                            diagram from
     in the diagram                          table 13.2
     to the right is the _____________________Vagus  page 437 of book
          lecture
29  (1) The structure extending down from this arrow 
      is the __________________sympathetic chain +/or trunk
                    or    paravertebral ganglia
          (figure was "sympathetic side" of fig 14.2, page 461)
    
The following is final exam section 3 from fall 1993, without answers
 5 ___  The event that resulted in the movement of one ancestral globin 
       gene to a different chromosome is best called 
       A) duplication         B) mutation     
       C) transposition  D) none of these
 6 ___  Which of the following is not true of complementary DNA?
       A) It can be amplified by polymerase chain reaction
       B) It can be used as a probe to locate a gene of interest
       C) It can be used to create a complete genomic library
       D) It eliminates the introns of eukaryotic genes
       E) It is produced from mRNA using reverse transcriptase
 7 ___  A paleontologist has recovered a bit of tissue from the 
     400-year-old preserved skin of an extinct dodo.  She would like 
     to compare DNA from the sample with DNA from living birds.  Which 
     of the following would be most useful for increasing the amount 
     of DNA available for testing?
       A) electroporation           
       B) gel electrophoresis     
       C) in situ hybridization     
       D) Polymerase chain reaction (PCR)     
       E) RFLP analysis
 8 ___  The Human Genome Project involves all of the following except
       A) altering the human genome
       B) the analysis of the genomes of other species
       C) the location of RFLP markers
       D) the physical mapping of the chromosomes
       E) the sequencing of the entire nucleotide sequence of our 
          genome
 9 ___  Chemical synapses are characterized by all of the following 
     except
       A) a fluid-filled gap separating the neurons
       B) ions flowing through protein channels from the presynaptic 
          to postsynaptic neuron
       C) postsynaptic membranes bearing receptors that bind 
          neurotransmitters.
       D) the release of neurotransmitter by the presynaptic membranes
10 ___  In the diagram to the right,
       which line ends in the cerebellum?
11 ___  The neural machinery of the spinal cord is at the
       A) programs level B) projection level 
       C) segmental level
12 ___  The portion of the fibrous tunic that is white and opaque is 
     the
       A) choroid   B) cornea    C) retina    D) sclera
  
16 (2) A woman with type O blood has 2 children with the same man.  
      One child has type O blood.  The other child has type B blood.
          What is the genotype of the father? _________________
          What is the phenotype of the father? ________________
17 (1) Sketch a diagram of a unipolar neuron.
18 (1) Define myelogram.
19 (2) Describe the formation of a spinal nerve.  That is, explain what 
      structures are located between the spinal cord and spinal nerve, 
     and how those structures are combined to form the spinal nerve.
20 (1) How is a receptor potential like an EPSP?
21 (1) Define vagotomy
Part 3, Diagrams.  (The point value of each question is in parenthesis)
22 (2) In the diagram below, line A ends in the ____________________
     and line B ends in the ________________________
23 (3) In this diagram of gene cloning
The molecule 
labeled A
is called 
_________________
The process
carried out 
in step B is
performed by
_________________
The process 
carried out 
in step C
is called
___________________
24 (1) The cell drawn to 
      the right is a(n)
      _________________
25 (1) The cells drawn 
      to the right are
      _________________
26 (2) Of the structures named below, which are commissures? 
     (Note: an equal amount of credit will be subtracted for each 
     wrong answer as is awarded for each correct answer.  The total 
     will be no worse that -2, that is, no credit for the question)
Write your anwswers in this space:
This is exam 3 from the morning class of Fall 1994
 6 ___    Proto-oncogenes become oncogenes by the process called
     A) duplication   B) homeotis  C) mutation       D) 
     transposition
     C lec
 7 ___    Which of the following tools of recombinant DNA technology
     is used to produce RFLPs?
     A) DNA ligase            B) DNA polymerase
     C) restriction enzyme         D) reverse transcriptase
     C lec and #1, chap 19
 8 ___    Which of the following is not part of the central nervous 
     system
     A) a nerve          B) the brain   C) the spinal cord
     D) none of these (that is, they are all part of the CNS)
     A lec and modified #1, chap 11
 9 ___    Which of these cells lines the brain cavities?
     A) astrocyte        B) ependymal cell        C) microglia
     D) oligodendrocyte  E) satellite cell        F) Schwann cell
     B lec and #2, chap 11
10 ___    Which of these cells myelinates nerve fibers in the CNS?
     A) astrocyte        B) ependymal cell        C) microglia
     D) oligodendrocyte  E) satellite cell        F) Schwann cell
     D lec and #2, chap 11
11 ___    An IPSP is inhibitory because it
     A) changes the threshold of the neuron
     B) hyperpolarizes the postsynaptic membrane
     C) prevents calcium ion entry into the presynaptic terminal
     D) reduces the amount of neurotransmitter released by the
          presynaptic terminal
     B lec and #11, chap 11
12 ___    L-Dopa is often used to treat which disease?
     A) Huntington's          B) multiple sclerosis
     C) Parkinson's      D) none of these
     C CT+A #3 chap 15
13 ___    Gustatory cells are stimulated by
     A) photons of light      B) stretch
     C) substances in solution     D) the movement of otoliths
     C lec and #4, chap 16
16 (2) Fetuses have a different hemoglobin than adults. How is the 
     fetal hemoglobin different physiologically (1), and why is that 
     physiologic difference important (1)?
     fetal Hb has a higher oxygen affinity
     in order to "steal" oxygen from the mother's blood
     lecture
17 (2) A woman with blood type A has two children with the same man.
     One has type O blood and the other has type B blood.
     What is the genotype of the father (1)? ___________IBi
          (use standard symbols or be sure to define your symbols!)
     What is the phenotype of the father (1)? ___________type B
     #6 chap 30
18 (1) Why must a DNA probe be used during human DNA fingerprinting
     procedures instead of simply observing RFLPs in a gel after
     electrophoresis?
     Because individual bands would not be visible on the gel
     lecture
19 (1) The brain area through which all sensory input 
     must travel to get to the cerebral cortex is the 
     __________________
     thalamus lec and #2, chap 12
20 (1) How is the limbic system important in behavior?
     It is the emotional brain 
     lec and #18, chap 12
21 (1) Define Paresthesia
     An abnomal sensation (burning, tingling) resulting from a 
     disorder of a sensory nerve  RTC chap 13
22 (1) Describe the basis of biofeedback training.
     The use of monitoring devices that provide 
     awareness of autonomic function
     #12, chap 14
25 (1) The figure below shows RFLP analysis of DNA extracted from
     blood of a murder victim, a suspect in the murder (defendant),
     and blood stains from the defendant's (suspect's) clothes.
     Explain clearly whether and why this evidence supports the
     guilt or innocence of the defendant.
     Clearly, the blood of the victim is the same as the blood found
     on the shirt of the defendant.  So, if you state that, and write 
     that this evidence supports the guilt of the defendant, you will
     get +1.
     If you go on and on, telling me how the fact that the number of
     comparisons (bands) are so few as to make this almost 
     meaningless,
     and that no control population was shown to be used to develop a
     percent probabilty of identity between victim's blood and shirt 
     blood,
     or bring up the fact that finding blood on a shirt owned by the
     defendant says NOTHING about whether the defendant was actually
     WEARING the shirt when the blood got on it (how many times have 
     you
     lent your shirt to a friend?) (cf. how many times have you lent
     your shirt AND JEANS to a friend), you will be proving that you
     understand the concept of innocent until PROVEN guilty, but you 
     won't
     gain (or lose) any points on the question.
     If you write that the pattern (absent) from blood on the 
     defendant's
     jeans is not the same as the victim's, and that this supports 
     the innocence of the defendant, you will get Zero credit.
     lecture
26 (1) Circle the area(s) in which neurotransmitters are stored in this
     motor neuron.
                    circle the right end of the diagram
                    the axon termini - ONLY  lecture
27 (1) The structure with 
     the asterisks (*)
     inside it is the
     ____________________
     corpus callosum 
     lec and #2, chap 12
28 (2) Which line 
     indicates a
     dorsal root
     ganglion?  ____
     2 lec and #24 chap 12 and #9, chap 13
     Which line 
     indicates a
     spinal nerve? ____
     4 lec and #9, chap 13
29 (1) On the diagram
     to the right, 
     circle the
     brachial plexus
     as specifically 
     as possible.
     the plexus in the region of the shoulder.
     lec and #13, chap 13
30 (1) Cranial nerve 10 (CN X)
     depicted in this figure
     is named the ___________
     nerve.
     vagus  lec and RTC chap 14
31 (1) The structure 
     labeled 2 is the
     
     _________________
     optic nerve  lecture
Part 4. Essay
32. (1) Briefly explain a potentially damaging or detrimental
     outcome of the production and use of herbicide resistant
     crop plants. (Grading key: If your answer is reasonably 
     correct, you may get one point. However, if your English 
     writing is poor, you may receive no credit. So, write a
     good, but brief, explanation)
     This raises the possibility of either home gardeners, 
     farmers or both releasing much more herbicide into the 
     environment,
     thus damaging either the ecosystem or specific plants or animals.
     OTHER ANSWERS ACCEPTABLE
     Stating that there is NO potential detriment receives Zero 
     credit.
     lecture
this is the evening exam 3 from fall 1994
 3 ___    Apparently, our muscle cells are different from our nerve
     cells mainly because they
     A) contain different genes         B) express different genes
     C) have different chromosomes 
     D) use different genetic codes
     B lec and #2 chap 18 Campbell
 4 ___    Alternate forms of the same gene are called
     A) alleles   B) autosomes   C) heterozygotes   D) homozygotes
     A) lecture and revised #1, chap 30
 5 ___    The brain cell diagrammed to the right is a
     A) bipolar neuron
     B) multipolar neuron
     C) unipolar neuron            table 11.1 top right
     D) none of the above
     C) unipolar lecture
 6 ___    The astrocyte shown 
     to the right of this line 
     is a
     A) bipolar neuron
     B) multipolar neuron
     C) unipolar neuron            figure 11.2 top left
     D) none of the above
     D lecture and #2, chap 11
 7 ___    An IPSP is inhibitory because it
     A) changes the threshold of the neuron
     B) hyperpolarizes the postsynaptic membrane
     C) prevents calcium ion entry into the presynaptic terminal
     D) reduces the amount of neurotransmitter released by the
          presynaptic terminal
     B lec and #11, chap 11
 8 ___    Cerebrospinal fluid is formed by
     A) arachnoid villi  B) choroid plexuses
     C) the dura mater   D) all of these
     B lec and #4 chap 12
 9 ___    The white matter areas within 
     the spinal cord to the right
     are called
     A) canals
     B) meninges
     C) nerves
     D) tracts
     D lecture
10 ___    Gastric motility and gastric secretions are increased by the
     A) cerebral cortex  B) parasympathetic division of ANS
     C) sympathetic division of ANS     D) none of these
     B lec and #2 chap 14
11 ___    The neural machinery of the spinal cord is at which level?
     A) programs    B) projection  C) segmental
     C. lec and #3 chap 15
12 ___    Gustatory cells are stimulated by
     A) photons of light      B) stretch
     C) substances in solution     D) the movement of otoliths
     C lec and #4 chap 16
17 (1) Clearly explain an example that indicates that different globin 
     proteins have different functions.
     alpha and beta globins are not interchangeable in
     a hemoglobin tetramer. OR
     Fetal hemoglobin, containing different globins than adult,
     has a higher oxygen affinity than adult.
     lecture
NOTE: The grading of question 18a depends on your answer to 18b.
     That is, a correct guess for the wrong reason will get zero 
     points!
18a (1) Suppose that you wish to accomplish "gene therapy" for a globin 
     protein abnormality by injecting a therapeutic recombinant DNA 
     into a fertilized egg which has defective globin genes. What 
     type of insert would you use in the therapeutic construct?  
     A) cDNA   B) genomic DNA  C) mRNA                 
     D) synthetic oligodeoxyribonucleotide (ODN)                  
                                  
18b (1) Explain clearly why that choice would be best.
     preferred answer is B (+1), so that the proper regulatory
     sequences would be present (+1) in the therapeutic DNA
     I will accept A, if you write that your vector would be
     engineered to have the proper regulatory sequences on it! (+2)
     I will not accept C or D.
     lecture
19 (1.5) Name and briefly describe the 3 stages of neuron development
     proliferation, during which the cells attain the correct number
     migration, during which the cells attain correct positions
     cellular differentiation, during which synapses are made and
          neurons specialize biochemically
     #25, chap 11
     
20 (0.5) What is the term used to describe the 
     outward folds or "ridges" of the cerebrum? 
     ____________________
     gyri. lec and #12 chap 12
21 (1) Name a commissure 
     in the diencephalon. _____________________
                       intermediate mass lec
22 (1) Spinal nerves divide 
     into structures called _________________
                       rami lec and #12, chap 13
23 (1) Define neurofibromatosis
     A genetic disorder characterized, in some sufferers, by
     tumors (neurofibromas) that may be grossly disfiguring.
     related clinical term, chap 13
26 (1) The sampling process
     shown to the right
     is called
     ____________________
     chorionic villi sampling lec
27 (3) These questions refer to 
     the steps in the diagram 
     to the right labeled with 
     the letter of the question
     A. The enzyme 
     used in step A is 
     A)____________________
     restriction enzyme 
     lec and #1 chap 19 Campbell
     B. The enzyme 
     used in step B is
     B) ____________________
     DNA ligase
     lec and #1, chap 19
     C. Step C is called _____
          1. cloning
          2. in situ hybridization
          3. reverse transcription
          4. transformation
               4. lecture
28 (1)
                         The structure running
                         along the right side of
                         the spinal cord in the
                         diagram is the
     
                         ________________________________________
                         sympathetic chain or trunk  lec
29 (1) The structure
     labeled 2 in 
     the diagram to 
     the right is the
     ___________________
     optic chiasm lec
Part 4. Essay
30. (1) Write a brief essay using effective English that explains how
       RFLP analysis can be misused to the detriment of people.
     (Grading key: If your answer is reasonably correct, you may get 
      one point. However, if your English writing is poor, you may 
      receive no credit. So, write a good, but brief, explanation.)
     THIS IS NOT AN OPINION QUESION, PER SE.  WRITING THAT RFLP 
     ANALYSIS
     CANNOT BE USED DETRIMENTALLY WILL RECEIVE ZERO CREDIT!
          RFLP analysis can be used as a method for discrimitation, 
     so that instead of "just" having race, religion, country of 
     national
     origin, physical challenges and other such discrimination 
     criteria,
     we will now be able to discriminate based AT LEAST on the exact 
     type
     of every single gene we inherit.  Someday, INTRON forms might 
     become
     in or out of fashion, depending on the "ruling" powers that be.
          OTHER ANSWERS ACCEPTABLE!
This is the fall 1994 final exam section 3, without answers
 4 _____  Homeotic genes are involved in providing or establishing
          A) hemoglobin       B) homeostasis
          C) overall body plan     D) tissues
 5 _____  Metastasis is
          A) a mutation activates a protooncogene
          B) loss of contact inhibition
          C) remission of a tumor to a stable condition
          D) the spread of cancer cells from their site of origin
          E) transformation of a cell into a cancer cell
 6 _____  Which of the following tools of recombinant DNA technology
     is incorrectly paired with its use?
          A) DNA ligase -- enzyme that cuts DNA
          B) DNA polymerase -- used in PCR
          C) electrophoresis -- DNA sequencing
          D) restriction enzyme -- production of RFLPs
          E) reverse transcriptase -- production of cDNA
 7 _____  Which of the following is not a technique for introducing
     recombinant DNA into host cells?
          A) electrophoresis
          B) infection by Agrobacterium
          C) infection by bacteriophage
          D) microinjection
          E) transformation using recombinant plasmids
 8 _____ The human genome project involves all of the following except
          A) altering the human genome
          B) the analysis of the genomes of other species
          C) the location of RFLP markers
          D) the physical mapping of the chromosomes
          E) the sequencing of the entire nucleotide
               sequence of the human genome
 9 _____  Which type of neuron
     is shown to the right?
          A) bipolar
          B) multipolar
          C) unipolar
10 _____  Which cell type myelinates nerve fibers in the CNS?
          A) astrocyte       B) ependymal      C) microglia
          D) oligodendrocyte    E) satellite    D) Schwann
11 _____  Brain area that controls temperature, hunger and water balance
          A) cerebellum       B) hypothalamus
          C) medulla               D) thalamus
12 _____  Taste buds are found on the
          A) anterior part of the tongue     B) palate
          C) posterior part of the tongue    D) all of these
19 (2)    A man and woman who both have blood type A have 5 children.
     The fifth has a medical condition requiring a blood 
     transfusion, and the parents learn that the child has
     blood type O. Upon learning that, the man claims that he
     cannot be the father of the type O child.
     Was the man's reaction justifiable genetically? Explain.
20 (1)    The template used to make cDNA is ___________________
21 (1)    What is the function of the PCR technique?
22 (2)    What causes cerebrovascular accidents (CVAs)?
     What are typically symptoms of CVAs?
23 (3)    List the structural components of the peripheral nervous
     system, and describe the function of each component.
24 (1)    The medical chart of a 68-year-old man includes the 
     following notes: "Slight tremor of right hand at rest; 
     stony facial expression; difficulty in initiating movements."
     Based on your present knowledge, what is the diagnosis?
27 (2)    Write the name of the
     molecules located in
     the circled organelle
     on the line leading to it.
     _________________________
     The blackened molecules in
     this region function as
     _________________________
28 (2) 
The blackened lobe
is called the
                                    This region is the
___________________
                                   _________________
29 (1)    The structure
     indicated by the
     thick line is the
     __________________
This is the Fall 1994 final exam section 3 WITH answers
 4 _____  Homeotic genes are involved in providing or establishing
          A) hemoglobin       B) homeostasis
          C) overall body plan     D) tissues
     C lecture handout
 5 _____  Metastasis is
          A) a mutation activates a protooncogene
          B) loss of contact inhibition
          C) remission of a tumor to a stable condition
          D) the spread of cancer cells from their site of origin
          E) transformation of a cell into a cancer cell
     D #5 chap 18 2E
 6 _____  Which of the following tools of recombinant DNA technology
     is incorrectly paired with its use?
          A) DNA ligase -- enzyme that cuts DNA
          B) DNA polymerase -- used in PCR
          C) electrophoresis -- DNA sequencing
          D) restriction enzyme -- production of RFLPs
          E) reverse transcriptase -- production of cDNA
     A lec and #1 chap 19
 7 _____  Which of the following is not a technique for introducing
     recombinant DNA into host cells?
          A) electrophoresis
          B) infection by Agrobacterium
          C) infection by bacteriophage
          D) microinjection
          E) transformation using recombinant plasmids
     A #2 chap 19
 8 _____ The human genome project involves all of the following except
          A) altering the human genome
          B) the analysis of the genomes of other species
          C) the location of RFLP markers
          D) the physical mapping of the chromosomes
          E) the sequencing of the entire nucleotide
               sequence of the human genome
     A #5 chap 19
 9 _____  Which type of neuron is shown to the right?
          A) bipolar
          B) multipolar
          C) unipolar
     B lecture handout!
10 _____  Which cell type myelinates nerve fibers in the CNS?
          A) astrocyte       B) ependymal      C) microglia
          D) oligodendrocyte    E) satellite    D) Schwann
     D lec and #2 chap 11
11 _____  Brain area that controls temperature, hunger and water balance
          A) cerebellum       B) hypothalamus
          C) medulla               D) thalamus
     B #2, chap 12 and lecture
12 _____  Taste buds are found on the
          A) anterior part of the tongue     B) palate
          C) posterior part of the tongue    D) all of these
     D #3, chap 16
19 (2)    A man and woman who both have blood type A have 5 children.
     The fifth has a medical condition requiring a blood 
     transfusion, and the parents learn that the child has
     blood type O. Upon learning that, the man claims that he
     cannot be the father of the type O child.
     Was the man's reaction justifiable genetically? Explain.
          NO! The man and woman could both be genotype iIA
     Grading key: I will not give partial credit if you guessed
     no, while not explaining it properly.
          #6, chap 30 (that is, revised question testing same 
     concepts)
20 (1)    The template used to make cDNA is ________mRNA_______
     lec and #1 chap 19
21 (1)    What is the function of the PCR technique?
     To amplify a specific fragment of DNA
     lec and #1 chap 19
22 (2)    What causes cerebrovascular accidents (CVAs)?
          Blockage of blood supply to a region of the brain (+1)
     What are typically symptoms of CVAs?
          paralysis and/or sensory deficits
               (only 1 needed for +1 point)
          Homework, chap 12
23 (3)    List the structural components of the peripheral nervous
     system, and describe the function of each component.
          nerves +.5 conduct information =.5
          sensory receptors +.5 respond to appropriate signal +.5
          motor endings +.5 stimulates muscles or glands +.5
     lecture and #9 chap 13
24 (1)    The medical chart of a 68-year-old man includes the 
     following notes: "Slight tremor of right hand at rest; 
     stony facial expression; difficulty in initiating movements."
     Based on your present knowledge, what is the diagnosis?
          Parkinsons CT+A #3 chap 15
27 (2)    Write the name of the
     molecules located in
     the circled organelle
     on the line leading to it.
     ___neurotransmitters__
     The blackened molecules in
     this region function as
     ______ion channels_____
     both lecture and some
     homework questions chap 11
28 (2) 
The blackened lobe
is called the____temporal____
                                                  
This region is the __cerebellum__
both lecture and some questions chap 12